Research topics at Molecular Mechanisms of Disease Group:
iPSCs disease modeling in a dish headed by Dr. Neli Kachamakova-Trojanowska
Pancreatic cancer research – role of the microenvironment headed by Dr. Monika Jakubowska
Head of the group:
Dr. Neli Kachamakova-Trojanowska
neli.kachamakova-trojanowska@uj.edu.pl,
phone: 12 664 6468, room 2/24
Team members:
Dr. Monika Jakubowska
Leader of the pancreatic cancer research
monika.jakubowska@uj.edu.pl
phone: 12 664 6468; room 2/24
Dr. Damian Klóska
topic: iPSCs disease modeling in a dish
damian.kloska@uj.edu.pl
phone: 12 664 6468; room 2/24
PhD student Kinga Stopa
kinga.stopa@doctoral.uj.edu.pl
(topic: pancreatic cancer)
PhD student Daria Krzysztofik
daria.krzysztofik@doctoral.uj.edu.pl
(topic: pancreatic cancer)
PhD student Dawid Skoczek
dawid.skoczek@doctoral.uj.edu.pl
(topic: iPSCs disease modeling)
Students:
Dominika Drapała
Filip Łoziński
Aldona Szewczyk
Funding:
2022-2024 Project PRELUDIUM 20, awarded to Daria Krzysztofik: "Long-term exposure to high copper: does it affect the production of pancreatic digestive enzymes?"
2021-2025 Project Sonata-Bis headed by Dr. Neli Kachamakova-Trojanowska: “Molecular background of microvascular complications in HNF1A-MODY patients: induced pluripotent stem cells as disease modeling tool”
2021-2022 POB BIOS Minigrant awarded to Dr. Monika Jakubowska
Title: "Copper misbalance and impaired exocrine pancreatic functions - ex vivo analyses of the Atp7b toxic milk mouse model"
2018-2021 Project OPUS headed by Dr. Neli Kachamakova-Trojanowska:“ Editing of HNF1A gene in human induced pluripotent stem cells with CRISPR/Cas9 for disease modeling of endothelial (dys)function in maturity onset diabetes of the young (MODY)”
2018-2020 Project HOMING headed by Dr. Monika Jakubowska: “Targeting mechanisms of pancreatic cancer resistance against therapy: specific role of tumor microenvironment”