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The Bionanoscience and Biochemistry laboratory is recruiting a doctoral student for a generous, fully-funded position with a duration of up to four years in project “efFect of nanoscale, three dimensional arrangement of proteins on biological and Therapeutic activity (FIT)”

The Bionanoscience and Biochemistry laboratory is recruiting a doctoral student for a generous, fully-funded position with a duration of up to four years in project entitled “efFect of nanoscale, three dimensional arrangement of proteins on biological and Therapeutic activity (FIT)”. The project aims to design and produce DNA and protein based artificial “smart” nanoparticles that will be able to prevent pathogenic bacteria from invading tissues and be able to deliver therapeutic molecules to diseased tissues.

The Bionanoscience and Biochemistry laboratory is recruiting a doctoral student for a generous, fully-funded position with a duration of up to four years in project entitled “efFect of nanoscale, three dimensional arrangement of proteins on biological and Therapeutic activity (FIT)”. The project aims to design and produce DNA and protein based artificial “smart” nanoparticles that will be able to

a) prevent pathogenic bacteria from invading tissues and

b) be able to deliver therapeutic molecules to diseased tissues.

 

The successful candidate will have the opportunity to work on all aspects of the project in what is a highly collaborative project. The main focus of the PhD project will aim at designing artificial protein and DNA nanoparticles able to block pathogenic bacteria form invading cells.
While working on the project, you will use in silico protein/DNA design techniques to design nanoparticles. You will use molecular biology and biochemistry techniques to produce particles. You will learn structural biology techniques such as Cryo-EM and other biophysical techniques to characterise your particles and cell biology techniques to assess their therapeutic potential. You will be given the opportunity to learn important soft skills such as presentation and management skills.  You will also be able to present your work at national and international conferences. You will be a valued member of the Bionanoscience and Biochemistry Laboratory which is an intellectually stimulating home to a vibrant group of bionanoscientists and biochemists.  

More information about the Bionanoscience and Biochemistry laboratory is available on Heddle Lab website.

The ideal candidate should fulfil the following criteria:

  • Possess master, master of an engineer or equivalent degree in molecular biology, protein engineering, structural biology, biochemistry or related areas;
  • Some experience in cell biology and cell culture techniques would be advantageous though not obligatory;
  • Be motivated to study biochemistry and structural biology and have an interest in inventing next generation smart drug delivery systems;
  • Have strong work commitment and the ability for independent work;
  • Have excellent written and oral communication skills in English;
  • Have good skills in work management and experimental record keeping;
  • Able to work across disciplines and be willing to gain expertise in new areas;
  • Able to work as a part of the team and with international collaborators.

For the details of the competition and required documentation go to the website of Doctoral School of Exact and Natural Sciences at the Jagiellonian University.