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Mostowy Lab | Microbial Genomics

Evolutionary genomics of infectious bacteria and viruses

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Microbial Genomics | Leader

dr hab. Rafał Mostowy

dr hab. Rafał Mostowy

Lider grupy badawczej Genomiki Mikroorganizmów w Małopolskim Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Principal Investigator

Rafał initially trained in theoretical physics at the Jagiellonian University (2002-2005) and the University of Copenhagen (2005-2007). In 2007 he joined the group of Sebastian Bonhoeffer at ETH Zurich to pursue a PhD in biology. After this, he received a Swiss National Science Foundation “Prospective Postdoc” fellowship to join the group of Christophe Fraser at Imperial College London. In 2013, he was awarded a Marie Skłodowska-Curie Intra-European Fellowship to work on the evolution of recombination in Streptococcus pneumoniae at Imperial College London, followed by an Imperial College Research Fellowship at the School of Public Health. In 2018, Rafał joined the Big Data Institute at the University of Oxford as a Senior Researcher in Bacterial Evolution, and early in 2019 he moved to Kraków to start the Microbial Genomics group.

Rafał is also a co-founder of Polonium Foundation, an organisation linking Polish researchers worldwide, and an co-author of a research study on the Polish Scientific Diaspora.

Bacteria are incredibly diverse and adaptable. This makes them exciting, but also problematic when they cause diseases. One notable example is resistance to antibiotics: as a result of excessive drug use, bacteria with the capacity to resist the action of antibiotics have been outcompeting other bacteria. As we are currently running out of antibiotics, we need novel weapons against these “superbugs”. But new weapons are not enough – bacteria will eventually overcome them too. Hence, we also need to understand how bugs adapt to these weapons and use them wisely.